Malegra 25 mg contains sildenafil citrate, a PDE5 inhibitor used to treat erectile dysfunction. Patients with severe hypotension (low blood pressure) should generally avoid Malegra 25 mg because sildenafil can further lower blood pressure by widening blood vessels. This can increase the risk of dizziness, fainting, shock, or even cardiovascular complications.

Specifically, Malegra 25 mg should be avoided by men who have:

Severe or uncontrolled low blood pressure (e.g., systolic BP < 90 mmHg)

A history of fainting or dizziness related to low blood pressure

Heart conditions that are worsened by low blood pressure, such as unstable angina or recent heart attack

Dehydration or severe blood loss, which can already reduce blood pressure

Severe liver or kidney disease, because these conditions can increase drug levels and worsen hypotension

Malegra 25 mg of nitrates or nitric oxide donors (e.g., nitroglycerin), as this combination can cause a dangerous and sudden drop in blood pressure

If a patient has severe hypotension but needs treatment for ED, they should consult a doctor for safer alternatives and careful monitoring. Do not self-medicate, especially with cardiovascular risks.