Recent Entries

• Bimekizumab Double Neutralizes IL-17A and IL-17F in Patients wi

  by Samantha James October 24, 2020
  Psoriasis is a chronic, immune-mediated inflammatory skin disease that affects up to 3% of the population and is associated with diseases including chronic lung disease, diabetes, liver disease, cardiovascular disease, chronic kidney disease, and rheumatic diseases There is a significant correlation...

• Something You Should Know About the Development Progress of Lip

  by Samantha James October 6, 2020
  Oxygenase exists in various plants, such as cereal seeds, soybeans, peas, and potatoes, with the highest content in soybeans. The presence of lipoxygenase in the food system can cause a decrease in the nutritional quality of the food and increase the difficulty of storage. Because lipoxygenase is st...

• The Workflow of PROTAC System (Part One)

  by Samantha James October 4, 2020
  In order to use the PROTAC system, it is necessary to develop a PROTAC that can target the target protein from scratch or modify the latter with tags (as described above) to degrade the molecules by HaloPROTAC or dTAG. Indeed, before developing PROTAC against endogenous proteins, it may be advantage...

• Targeted Proteolytic Chimera (PROTAC) As A Therapeutic Tool (Pa

  by Samantha James October 3, 2020
   The role of FAK scaffolding is essential for cell migration, but essential for proliferation Given that patient studies with focal adhesion kinase (FAK) inhibitors failed to fulfill their preclinical promises, Cromm et al. (2018) FAK inhibitor defactinib was incorporated into PROTAC to ev...

• Magical Peptides and Their Functions (II)

  by Samantha James September 29, 2020
  Main applications At present, the application of functional peptides is mainly in the following aspects: 1. Functional foods: peptide foods with certain functions are currently a hotspot in international research. Japan, the United States, and Europe have taken the lead in launching food and foo...